I'm familiar with this use case, and it was one of the reasons for the redesign of NAIL in VQMS 5.3. I forgot that Raymond James is still using 5.2, so now I understand your source of confusion. Let me explain.
In NAIL for VQMS 5.2 (now known as NAIL2), there are frequently incompatibilities with the NAIL driver implementation and certain routers. Sometimes this incompatibility manifests itself as an inability to RDP from the user browser to the deployed VM when the end user is on the same subnet as the external IP address of the deployed VM. The incompatibility would also manifest itself as a failure to connect from a deployed VM of one deployment group (e.g. one of the tester workstation VMs) to a deployed VM of another deployment group (e.g. a web server deployed as part of your multi-server application to test.) Without sharing too many gory details, the incompatibility is rooted in how the NAIL driver sends all external traffic to the default gateway regardless of destination subnet, and some default gateways don't like this. As you are probably familiar, we usually work around the problem by configuring the network such that VMs are deployed onto a dedicated VLAN (the "VR network") separated from everything else. But the workaround gets much more complicated to solve your use case as it requires multiple VLANs and multiple pools of resources.
In NAIL for VQMS 5.3 (aka NAIL3), the potential for incompatibility is removed because NAIL driver is no longer used, and the NAIL server can distiguish network traffic properly. I.e., external network communication that is destined to the same subnet--like one deployed VM talking to another VM deployed in another deployment group--does not get sent to the default gateway.